Thus, topical calcipotriene may be used as an alternative or adjunct to topical corticosteroid therapy. It is applied twice daily when used as monotherapy. No controlled trials guide how best to use topical corticosteroids in conjunction with calcipotriene. Once daily use of each may be adequate. Acidic products can inactivate topical calcipotriene, and some topical corticosteroids may be acidic. A reasonable approach to combination therapy is to have patients apply topical calcipotriene and topical corticosteroids each once daily at different times of day.
The Humane Society of the United States says that a bear gallbladder can cost more than $3,000 in Asia, where some people use the organ for medicinal purposes. "Bear gallbladders and bile are used in traditional medicine to treat a variety of illnesses including fever, liver disease, convulsions, diabetes, and heart disease," HSUS' website states . "Clinical research analyzing the medicinal properties of bear gallbladders indicates that they may be effective for treating a number of ills. However, other natural substances already accepted in traditional medicine, as well as synthetic substances, can be substituted."